Test The Effectiveness Of Japanese Papaya Leaf Extract (Cnidoscolus aconitifolius) On Aedes aegypti Larvae Mortality

Dengue hemorrhagic fever (DHF) is caused by the dengue virus which transmitted through bite of Aedes aegypti mosquito. Prevention DHF can be done using larvicides. Synthetic chemical larvicides are considered to have side effects in long-term use and cause environmental pollution. So we need an alternative with natural ingredients from plants, namely Japanese Papaya plants. This study aims determine effectiveness (Cnidoscolus aconitifolius) leaf extract on mortality larvae. type research uses experimental design. used 6 treatments 4 repetitions consisting control without treatment, P1 (0.2%), P2 (0.4%), P3 (0.6%), P4 (0.8%), P5 (1%). Observations were made for 48 hours. From results obtained LC50 1.095%. The statistical tests One-Way ANOVA showed that there was a significant effect mosquito larvae.